Horned-Viper Bite: A Clinical Case and Review of Therapeutic Approach

Authors

  • Cristiano Gante Serviço Medicina Interna 1. Unidade Local de Saúde São José. Lisboa. https://orcid.org/0009-0004-8238-0293
  • Adriana Watts Soares Serviço Medicina Interna 1. Unidade Local de Saúde São José. Lisboa. https://orcid.org/0000-0002-6166-3145
  • João Brazete Serviço Cirurgia Plástica e Reconstrutiva. Unidade Local de Saúde São José. Lisboa.
  • Rafael Terceiro Centro de Medicina Subaquática e Hiperbárica. Hospital das Forças Armadas. Pólo de Lisboa. Lisboa.
  • Fátima Rato Centro de Informação Antivenenos. Instituto Nacional de Emergência Médica. Lisboa.

DOI:

https://doi.org/10.20344/amp.24300

Keywords:

Antivenins, Disseminated Intravascular Coagulation, Hyperbaric Oxygenation, Snake Bites

Abstract

Envenomation by the horned viper (Vipera latastei), endemic to the Iberian Peninsula, typically causes local and hematologic toxicity, potentially leading to venom-induced consumption coagulopathy. We report the case of a 39-year-old man bitten on the fourth finger of his left hand. The first dose of antivenom (ViperFav®) was administered 10 hours after the incident, followed by two additional doses due to persistent coagulopathy and transient thrombocytopenia. Hyperbaric oxygen therapy (10 sessions) and a transdermal nitroglycerin patch were used to optimize local perfusion as adjuvant therapies that are still discussed in the medical literature. Clinical evolution was favorable, with preservation of finger viability and progressive laboratory recovery. This case highlights the importance of early antivenom administration, continuous hematologic monitoring, and the potential benefits of integrating adjuvant therapies to prevent necrosis and systemic complications. A multidisciplinary approach enabled full functional recovery without sequelae.

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References

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Published

2026-06-01

How to Cite

1.
Gante C, Watts Soares A, Brazete J, Terceiro R, Rato F. Horned-Viper Bite: A Clinical Case and Review of Therapeutic Approach. Acta Med Port [Internet]. 2026 Jun. 1 [cited 2026 Jun. 5];39(6-7):405-8. Available from: https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/24300

Issue

Section

Case Report