Review of Reviews (Umbrella Reviews): Step-by-Step Guide


  • Helena Donato Serviço de Documentação e Informação Científica. Hospitais da Universidade de Coimbra. Unidade Local de Saúde de Coimbra. Coimbra; Faculdade de Medicina. Universidade de Coimbra. Coimbra.
  • Mariana Donato Serviço de Otorrinolaringologia. Unidade Local de Saúde Lisboa Ocidental. Lisboa; NOVA Medical School. Lisboa.



Research Design, Review Literature as Topic, Systematic Reviews as Topic


In recent years, as a result of the dramatic increase in the number of systematic reviews, a new type of systematic review, the ‘systematic reviews of systematic reviews’, also known as umbrella reviews, reviews of reviews, meta-reviews or synthesis of review, was developed. The aim of this article is to provide recommendations on how this type of systematic review should be conducted and reported to ensure its quality and usefulness. These reviews are designed to compile evidence from multiple systematic reviews of interventions into an accessible and usable document and are one of the highest levels of evidence synthesis.


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How to Cite

Donato H, Donato M. Review of Reviews (Umbrella Reviews): Step-by-Step Guide. Acta Med Port [Internet]. 2024 Jul. 1 [cited 2024 Jul. 25];37(7-8):547-55. Available from:



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