TY - JOUR AU - Macedo, A AU - Agualusa, A AU - Kaku, S AU - Lima, M AU - Cabrita, J AU - Bento, R AU - Sampayo, F PY - 1991/12/31 Y2 - 2024/03/28 TI - Endocarditis caused by Candida parapsilosis after total correction of tetralogy of Fallot. Medico-surgical treatment. JF - Acta Médica Portuguesa JA - Acta Med Port VL - 4 IS - 6 SE - DO - 10.20344/amp.3377 UR - https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/3377 SP - 301-4 AB - Three children with Candida Parapsilosis endocarditis after total surgical correction for Tetralogy of Fallot, are reported. Blood cultures became negative in one child with amphotericin-B and in the other two with Ketoconazole, before reoperation for septal patch replacement. Oral therapy with Ketoconazole continued for a total of 24 months, and during a mean follow-up of 36 months no side effects or reinfection occurred. Medical and surgical conjoined therapy, with surgical timing decided on clinical and laboratorial grounds, were important for good results and cure. ER -