Infectious Mononucleosis and Cholestatic Hepatitis: A Rare Association

Authors

  • Catarina Salgado Departamento de Pediatria. Hospital de Santa Maria. Centro Hospitalar Lisboa Norte. Lisboa.
  • Ana Margarida Garcia Departamento da Mulher, Criança e Adolescente. Centro Hospitalar Lisboa Central. Lisboa.
  • Catarina Rúbio Serviço de Pediatria. Hospital Vila Franca de Xira. Vila Franca de Xira.
  • Florbela Cunha Serviço de Pediatria. Hospital Vila Franca de Xira. Vila Franca de Xira.

DOI:

https://doi.org/10.20344/amp.8715

Keywords:

Adolescent, Cholestasis, Epstein-Barr Virus Infections, Hepatitis, Infectious Mononucleosis

Abstract

Infectious mononucleosis is one of the major clinical manifestations of Epstein-Barr virus infection. In this syndrome, elevation of liver transaminase levels is common but cholestasis is rare, with few cases described in the literature. We present the case of a 14-year-old female adolescent, admitted to the Emergency Room with fever, odynophagia and cervical adenomegaly. She was treated with amoxicillin and two days later he presented with jaundice. The analytical evaluation was compatible with cholestatic hepatitis and abdominal ultrasound revealed hepatosplenomegaly without dilatation of the bile ducts. The diagnosis of Epstein-Barr virus infection was confirmed by the presence of serological markers. This case aims to raise awareness of a rare manifestation of a common infectious agent and, consequently, to the inclusion of acute Epstein-Barr virus infection in the differential diagnosis of pediatric cholestatic hepatitis.

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Published

2017-12-29

How to Cite

1.
Salgado C, Garcia AM, Rúbio C, Cunha F. Infectious Mononucleosis and Cholestatic Hepatitis: A Rare Association. Acta Med Port [Internet]. 2017 Dec. 29 [cited 2024 Jul. 25];30(12):886-8. Available from: https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/8715

Issue

Section

Case Report