Therapeutic perspectives of HIV infection and of opportunistic infections. Multicenter projects of clinical investigation in the EEC.

F Antunes

Abstract


Some centers in Portugal involved in the treatment of AIDS patients collaborate in clinical research programmes at a European level. The European Network for the Treatment of AIDS (ENTA) is a concerted action, with logistical and political support from the European Community. Four prospective European multicentre trials on opportunist infections in AIDS patients, have been implemented since the beginning of the ENTA, and 45 European centres, belonging to 11 countries, including Portugal, are so far involved in the present Trials in the Treatment and Prophylaxis of Tuberculosis and Toxoplasmosis. EUROAIDS is another concerted action whose aim is a retrospective study on opportunist infections and cancers related with AIDS registered in several countries in Europe, from 1979 to 1989, and correlate these data with demographic and clinical aspects. Another multicentric trial on antiretroviral treatment, The Iberian ddI study, started and several Spanish and Portuguese centres enrolled patients in this study.

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