Sulpiride stimulation of prolactin secretion in adolescents with gynecomastia: relation to the circulating levels of estradiol.

Hugo L. Fideleff; Silvia Belma; Abraham Guitelman; Ana Maria Baigorri; Daniel Aquilano; Hugo E. Scaglia

doi:10.20344/amp.4170

Sulpiride stimulation of prolactin secretion in adolescents with gynecomastia: relation to the circulating levels of estradiol.

Authors

Hugo L. Fideleff Unidad endocrinologia, Hospital Dr. T. Alvarez, Buenos Aires y Centro de Referencia de RIA. Distrito 1 de ia Federacion Bioquimica de ia Provincia de Buenos Aires. La Plata. Argentina.
Silvia Belma Unidad endocrinologia, Hospital Dr. T. Alvarez, Buenos Aires y Centro de Referencia de RIA. Distrito 1 de ia Federacion Bioquimica de ia Provincia de Buenos Aires. La Plata. Argentina.
Abraham Guitelman Unidad endocrinologia, Hospital Dr. T. Alvarez, Buenos Aires y Centro de Referencia de RIA. Distrito 1 de ia Federacion Bioquimica de ia Provincia de Buenos Aires. La Plata. Argentina.
Ana Maria Baigorri Unidad endocrinologia, Hospital Dr. T. Alvarez, Buenos Aires y Centro de Referencia de RIA. Distrito 1 de ia Federacion Bioquimica de ia Provincia de Buenos Aires. La Plata. Argentina.
Daniel Aquilano Unidad endocrinologia, Hospital Dr. T. Alvarez, Buenos Aires y Centro de Referencia de RIA. Distrito 1 de ia Federacion Bioquimica de ia Provincia de Buenos Aires. La Plata. Argentina.
Hugo E. Scaglia Unidad endocrinologia, Hospital Dr. T. Alvarez, Buenos Aires y Centro de Referencia de RIA. Distrito 1 de ia Federacion Bioquimica de ia Provincia de Buenos Aires. La Plata. Argentina.

DOI:

https://doi.org/10.20344/amp.4170

Abstract

Basal levels of prolactin (PRL) and estradiol (E₂) were studied in 10 adolescents with gynecomastia who were at stages II to IV of their sexual development. In 7 of the 10 patients, the hypophyseal response of PRL to the administration of sulpiride was assessed: 5 of the 7 received 25 mg i.m., and the remaining 50 mg. i.m. The 10 cases were compared with 12 control boys without gynecomastia matched for stage of sexual development. Five of the controls were given 25 mg of sulpiride i.m. and the other 50 mg. Basal PRL levels were the same in both groups. Sulpiride stimulates the secretion of PRL in boys with and without gynecomastia. However, a significantly increased circulating E₂ level was found in patients with gynecomastia.

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How to Cite

Fideleff HL, Belma S, Guitelman A, Baigorri AM, Aquilano D, Scaglia HE. Sulpiride stimulation of prolactin secretion in adolescents with gynecomastia: relation to the circulating levels of estradiol. Acta Med Port [Internet]. 1980 Aug. 31 [cited 2024 Apr. 16];2(4):269-73. Available from: https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/4170

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Issue

Vol. 2 No. 4 (1980): Julho - Agosto

Section

Arquivo Histórico

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