Alcohol and liver damage.

Sheila Sherlock

Abstract


The association of alcohol with cirrhosis was recognised by Matthew Baillie in 1793 and later by Addison. In Western countries the incidence of cirrhosis can be directly related to the quantity of alcohol consumed. In France, between - 1941 and 1947, rationing of wine from five to one litre per week led to an 80% reduction in mortality from cirrhosis. Cirrhosis is on the increase. In the U.S.A. it is the fourth commonest cause of death in white males. In Britain, deaths from cirrhosis have increased by approximately 25% in the last decade. The death rate in different communities correlates quite well with alcohol consumption 


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