Methods for preserving bone marrow for autologous transplantation.


  • F L da Costa Unidade de Transplantação de Medula Ossea (UTMO) do Hospital de Santa Maria, Lisboa.
  • P Pimentel
  • A Tavares
  • C Juncal
  • J M Lacerda



For Autologous Bone Marrow Transplantation (ABMT) the patient's own marrow is harvested before myelotoxic high-dose radio-chemotherapy and later returned to promote hemopoietic reconstitution. Between harvest and return the bone marrow must be preserved. The time elapsed between harvest and return depends on the intended therapy. Although--bone marrow may keep its hematopoietic potential for a few days without freezing, preservation for longer periods imposes the need for cryopreservation. Some of the current methods for marrow preservation are reviewed, with special emphasis given to cryopreservation. Hospital de Santa Maria Bone Marrow Transplant Unit cryopreservation method is described.


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How to Cite

da Costa FL, Pimentel P, Tavares A, Juncal C, Lacerda JM. Methods for preserving bone marrow for autologous transplantation. Acta Med Port [Internet]. 1992 Feb. 27 [cited 2024 Apr. 21];5(2):79-85. Available from:



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