Aplastic anemia. Alternative treatment by bone marrow transplantation.

Authors

  • T Fonseca Serviço Medicina I, Hospital de Santa maria, Lisboa.
  • J Raposo
  • B Gomez
  • J J d'Oliveira
  • J M de Lacerda

DOI:

https://doi.org/10.20344/amp.2372

Abstract

We report a case of a 25-year-old woman, with the diagnosis of severe aplastic anemia without a histocompatible sibling donor for bone marrow transplantation. The patient has been treated successfully with a combination of two immunosuppressive agents, cyclosporine and antilymphocyte globulin, after not responding to primary therapy with corticosteroids and growth factors. She showed a complete response to treatment, with transfusional independence, after a follow-up of 14 months. The pathophysiology of aplastic anemia, the mechanism of action and secondary effects of these treatments are discussed.

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How to Cite

1.
Fonseca T, Raposo J, Gomez B, d’Oliveira JJ, de Lacerda JM. Aplastic anemia. Alternative treatment by bone marrow transplantation. Acta Med Port [Internet]. 1997 Jan. 30 [cited 2024 Mar. 29];10(1):99-102. Available from: https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/2372

Issue

Section

Arquivo Histórico