Ocular Tuberculosis in Pediatrics: A Case Report





Adolescent, Tuberculosis, Ocular/diagnosis, Uveitis/diagnosis


A 17-year-old male was taken to the emergency department for decreased left visual acuity and floaters beginning that same day. There was a history of exposure to pulmonary tuberculosis five years before (mother as index case) followed by a four-month period of isoniazid prophylaxis. The ophthalmic examination showed posterior and intermediate uveitis in the left eye. Laboratory tests were normal; IgG for herpes simplex 1 was positive and both the varicella-zoster virus and remaining serologic tests were negative. Chest radiography was normal. Two weeks later, an epiretinal membrane with risk of tractional retinal detachment was observed. The Mantoux tuberculin skin test showed an induration of 15 mm and the IGRA test was positive. Sputum and vitreous humor samples were collected. Quadruple therapy and prednisolone were started. Ten days later, a posterior vitreous detachment with underlying vitreous hematoma was observed. Posterior vitrectomy and peripheral endolaser were performed without complications. One month later, the microbiological results became available, with the identification of Mycobacterium tuberculosis. Corticosteroids were weaned progressively. Antituberculous drugs were maintained for six months. The patient made a full recovery.


Download data is not yet available.


Teixeira-Lopes F, Alfarroba S, Dinis A, Gomes MC, Tavares A. Ocular tuberculosis – a closer look to an increasing reality. Pulmonology. 2018;24:289-93. DOI: https://doi.org/10.1016/j.pulmoe.2018.02.006

Haq A, Shaheen F, Farooq S. Various spectrum of ocular tuberculosis. J Ayub Med Coll Abbottabad. 2021;33:332-4.

Figueira L, Fonseca S, Ladeira I, Duarte R. Ocular tuberculosis: position paper on diagnosis and treatment management. Rev Port Pneumol. 2017;23:31-8. DOI: https://doi.org/10.1016/j.rppnen.2016.10.004

Marin-Acevedo JA, Chirila RM, Cowart JB. Ocular tuberculosis. J Gen Intern Med. 2019;34:2288-9. DOI: https://doi.org/10.1007/s11606-019-05129-w

Testi I, Agrawal R, Mehta S, Basu S, Nguyen Q, Pavesio C, et al. Ocular tuberculosis: where are we today? Indian J Ophthalmol. 2020;68:1808-17. DOI: https://doi.org/10.4103/ijo.IJO_1451_20

Shakarchi FI. Ocular tuberculosis: current perspectives. Clin Ophthalmol. 2015;9:2223-7. DOI: https://doi.org/10.2147/OPTH.S65254

Hamade IH, Tabbara KF. Complications of presumed ocular tuberculosis. Acta Ophthalmol. 2010;88:905-9. DOI: https://doi.org/10.1111/j.1755-3768.2009.01579.x

Gunasekeran DV, Gupta B, Cardoso J, Pavesio CE, Agrawal R. Visual morbidity and ocular complications in presumed intraocular tuberculosis: an analysis of 354 cases from a non-endemic population. 2017;26:865-9. DOI: https://doi.org/10.1080/09273948.2017.1296580

Rosenbaum JT. Uveitis: etiology, clinical manifestations, and diagnosis. UpToDate. [consultado 2021 dez 15]. Disponível em: https://www.uptodate.com/contents/uveitis-etiology-clinical-manifestations-and-diagnosis?search=uveitis&source=search_result&selectedTitle=1~150&usage_type=default&display_rank=1#H3.

Shukla D, Kalliath J, Dhawan A. Tubercular retinal vasculitis: diagnostic dilemma and management strategies. Clin Ophthalmol. 2021;15:4681. DOI: https://doi.org/10.2147/OPTH.S284613

Adams LV, Starke JR. Tuberculosis disease in children. UpToDate. [consultado 2022 dez 10]. Disponível em: https://www.uptodate.com/contents/tuberculosis-disease-in-children?search=tuberculosis&source=search_result&selectedTitle=1~150&usage_type=default&display_rank=1#H10.

Neuhouser AJ, Sallam A. Ocular tuberculosis. StatPearls. Treasure Island: Stat Pearls Publishing; 2022.

Bigdon E, Steinhorst NA, Weissleder S, Durchkiv V, Stübiger N. Treatment in latent tuberculosis uveitis - is immunosuppression effective or is conventional 3- or 4-drug antituberculosis therapy mandatory? J Clin Med. 2022;11:2419. DOI: https://doi.org/10.3390/jcm11092419



How to Cite

Vieira PM, Zilhão C, Miranda V. Ocular Tuberculosis in Pediatrics: A Case Report. Acta Med Port [Internet]. 2023 Apr. 19 [cited 2023 Sep. 23];. Available from: https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/19245



Case Report