Multiple Myeloma Treatment Guidelines by the Portuguese Group of Multiple Myeloma

Authors

  • Cristina João Serviço de Hemato-Oncologia. Fundação Champalimaud. Lisboa; NOVA Medical School. Universidade NOVA de Lisboa. Lisboa. https://orcid.org/0000-0002-3978-766X
  • Rui Bergantim Serviço de Hematologia. Centro Hospitalar São João. Porto; i3S - Instituto de Investigação e Inovação em Saúde. Universidade do Porto. Porto; Cancer Drug Resistance Group. IPATIMUP – Instituto the Patologia Molecular e Imunologia. Universidade do Porto. Porto.
  • Joana Santos Serviço de Hematologia. Centro Hospitalar Lisboa Central. Lisboa.
  • Celina Afonso Serviço de Hematologia Clínica. Centro Hospitalar Lisboa Ocidental. Lisboa.
  • Paulo Bernardo Serviço de Hematologia Clínica. Hospital da Luz Lisboa. Lisboa.
  • Henrique Coelho Serviço de Hematologia Clínica. Centro Hospitalar Vila Nova Gaia. Gaia.
  • Carlos Costa Hematologia Clínica. Instituto CUF Oncologia. Lisboa.
  • Graça Esteves Serviço de Hematologia e Transplante de Medula. Centro Hospitalar Universitário Lisboa Norte. Lisboa.
  • José Guilherme Freitas Serviço de Onco-Hematologia. Instituto Português de Oncologia do Porto. Porto.
  • Rita Gerivaz Serviço de Hematologia. Hospital Garcia de Orta. Almada.
  • Ana Jorge Serviço de Hematologia Clínica. Centro Hospitalar Lisboa Ocidental. Lisboa.
  • Ana Macedo Serviço de Hematologia. Centro Hospitalar Universitário do Algarve. Algarve; Faculdade de Ciências da Saúde. Universidade da Beira Interior. Covilhã.
  • Ana Montalvão Unidade de Hematologia-Oncologia. Unidade Local de Saúde do Baixo Alentejo. Beja; Hospital de José Joaquim Fernandes. Beja.
  • Manuel Neves Serviço de Hemato-Oncologia. Fundação Champalimaud. Lisboa.
  • Claúdia L. Pedrosa Serviço de Hematologia Clínica. Centro Hospitalar Universitário do Porto. Porto.
  • Susana Pereira Serviço de Hematologia. Hospital Santo António dos Capuchos. Centro Hospitalar Universitário Lisboa Central. Lisboa.
  • Adriana Roque Serviço de Hematologia Clínica. Centro Hospitalar e Universitário de Coimbra. Coimbra; Instituto de Fisiologia. Faculdade de Medicina. Universidade de Coimbra. Coimbra.
  • Patrícia Seabra Serviço de Hematologia Clínica. Centro Hospitalar Universitário do Porto. Porto.
  • Helena M. Silva Serviço de Hematologia. Centro Hospitalar Tondela-Viseu. Viseu.
  • Maria P. Silveira Hematologia Clínica. Clínica de Oncologia e Radioterapia. Centro Clínico SAMS. Lisboa; Serviço de Imuno-Hemoterapia. Hospital Prof. Doutor Fernando da Fonseca. Amadora.
  • Ana Tomé Serviço de Hematologia. Hospital Garcia de Orta. Almada.
  • Fernanda Trigo Serviço de Hematologia. Centro Hospitalar São João. Porto.
  • Ana Bela Sarmento Serviço de Hematologia Clínica. Centro Hospitalar e Universitário de Coimbra. Coimbra; Laboratório de Oncobiologia e Hematologia. Clínica Universitária de Hematologia e Instituto de Investigação Clínica e Biomédica de Coimbra. Grupo de Investigação em Ambiente, Genética e Oncobiologia. Faculdade de Medicina. Universidade de Coimbra. Coimbra; Centro Académico Clínico de Coimbra. Coimbra. 
  • Paulo Lúcio Serviço de Hemato-Oncologia. Fundação Champalimaud. Lisboa.
  • Catarina Geraldes Serviço de Hematologia Clínica. Centro Hospitalar e Universitário de Coimbra. Coimbra; Laboratório de Oncobiologia e Hematologia. Clínica Universitária de Hematologia e Instituto de Investigação Clínica e Biomédica de Coimbra. Grupo de Investigação em Ambiente, Genética e Oncobiologia. Faculdade de Medicina. Universidade de Coimbra. Coimbra; Centro Académico Clínico de Coimbra. Coimbra. 
  • em representação do GRUPO PORTUGUÊS DO MIELOMA MÚLTIPLO

DOI:

https://doi.org/10.20344/amp.19037

Keywords:

Multiple Myeloma/drug therapy, Portugal

Abstract

The treatment of multiple myeloma has profoundly changed with the introduction of several innovative therapies. The optimization of therapeutic sequencing through the combined use of the various drugs developed in recent years and the attention given to the characteristics of patients have allowed the reduction of toxicities and increased survival and quality of life of patients with multiple myeloma. These treatment recommendations from the Portuguese Multiple Myeloma Group offer guidance for first-line treatment and progression/relapse situations. These recommendations are given highlighting the data that justify each choice and referring to the respective levels of evidence that support these options. Whenever possible, the respective national regulatory framework is presented. These recommendations constitute an advance towards the best treatment of multiple myeloma in Portugal.

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Published

2023-07-03

How to Cite

1.
João C, Bergantim R, Santos J, Afonso C, Bernardo P, Coelho H, Costa C, Esteves G, Freitas JG, Gerivaz R, Jorge A, Macedo A, Montalvão A, Neves M, Pedrosa CL, Pereira S, Roque A, Seabra P, M. Silva H, Silveira MP, Tomé A, Trigo F, Sarmento AB, Lúcio P, Geraldes C, em representação do GRUPO PORTUGUÊS DO MIELOMA MÚLTIPLO. Multiple Myeloma Treatment Guidelines by the Portuguese Group of Multiple Myeloma. Acta Med Port [Internet]. 2023 Jul. 3 [cited 2024 Apr. 25];36(7-8):517-26. Available from: https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/19037

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Section

Guidelines