Anemia in Chronic Kidney Disease: The State of the Art
Keywords:Anemia/diagnosis, Anemia/drug therapy, Anemia, Iron-Deficiency, Prolyl-Hydroxylase Inhibitors/therapeutic use, Renal Insufficiency, Chronic/complications
AbstractThe aging of the population has led to an increased prevalence of chronic diseases such as chronic kidney disease. Anemia is one of the most frequent complications of chronic kidney disease, with an impact not only on the quality of life but also on the patient’s prognosis and associated costs. Knowledge in this therapeutic area has increased significantly: from the appearance of recombinant erythropoietin in 1989, through the use of increasing doses of parenteral iron and, more recently, to new molecules such as hypoxia-inducible factor inhibitors. The aim of this article is to present a pragmatic review of the state of the art in the epidemiology, pathophysiology, diagnosis and treatment of anemia associated with chronic kidney disease.
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