Invasive Pleomorphic Lobular Carcinoma of The Male Breast: A Rare Diagnosis with Radiologic-Pathologic Correlation

Authors

  • Marta Costa Serviço de Radiologia. Centro Hospitalar Universitário de Lisboa Central. Lisboa. https://orcid.org/0000-0001-7168-5826
  • Beatriz Costeira Serviço de Cirurgia Geral. Instituto Português de Oncologia de Lisboa Francisco Gentil. Lisboa.
  • Ricardo Fonseca Serviço de Anatomia Patológica. Instituto Português de Oncologia de Lisboa Francisco Gentil. Lisboa.
  • José Carlos Marques Serviço de Radiologia. Instituto Português de Oncologia de Lisboa Francisco Gentil. Lisboa.

DOI:

https://doi.org/10.20344/amp.17206

Keywords:

Breast Neoplasms, Male, Carcinoma, Lobular Magnetic Resonance Imaging, Mammography

Abstract

Male breast cancer is a rare disease, representing approximately 1% of all breast cancers, but its incidence appears to be increasing over the years. As normal male breast does not develop acini and lobules, lobular carcinoma is very rare, accounting for 1% - 2% of all cases of male breast cancer. Pleomorphic lobular carcinoma is an aggressive variant of invasive lobular carcinoma with only six cases of male breast reported in the literature until now, and none with associated Paget’s disease. We report a case of an invasive pleomorphic lobular carcinoma with axillary lymph node involvement and associated Paget’s disease in a high-risk man. Low awareness among men and a lack of a screening program often lead to a late diagnosis of male breast cancer, and consequently, at a later stages of disease, with lower survival rates compared to women. Early diagnosis is essential in order to improve patient outcomes and achieve better survival rates in men.

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References

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Published

2022-03-07 — Updated on 2022-03-07

How to Cite

1.
Costa M, Costeira B, Fonseca R, Marques JC. Invasive Pleomorphic Lobular Carcinoma of The Male Breast: A Rare Diagnosis with Radiologic-Pathologic Correlation. Acta Med Port [Internet]. 2022 Mar. 7 [cited 2022 Dec. 7];35(11):840-4. Available from: https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/17206

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Section

Case Report