Inflammatory Myofibroblastic Tumour of the Common Bile Duct

Authors

  • Matilde Almeida e Sousa Serviço de Radiologia. Centro Hospitalar Universitário Lisboa Central. Lisboa. Departamento de Anatomia e Imagiologia Clínicas. NOVA Medical School. Lisboa.
  • Ana Carvalho Serviço de Anatomia Patológica. Hospital Curry Cabral. Centro Hospitalar Universitário Lisboa Central. Lisboa.
  • Raquel Mega Unidade Hepato-bilio-pancreática. Hospital Curry Cabral. Centro Hospitalar Universitário Lisboa Central. Lisboa.
  • Tiago Bilhim Serviço de Radiologia. Centro Hospitalar Universitário Lisboa Central. Lisboa. Departamento de Anatomia e Imagiologia Clínicas. NOVA Medical School. Lisboa. Unidade de Radiologia de Intervenção. Hospital Curry Cabral. Centro Hospitalar Universitário Lisboa Central. Lisboa.

DOI:

https://doi.org/10.20344/amp.16976

Keywords:

Bile Duct Neoplasms, Hepatic Duct, Common, Hepatectomy, Klatskin Tumour, Liver Function Tests

Abstract

Inflammatory myofibroblastic tumour is a rare entity of indeterminate biological potential with a reduced tendency for recurrence and metastasis. Although it can arise from multiple organs, the bile duct is a very rare site of origin. We report the case of a 75-year-old asymptomatic male with elevated gamma-glutamyl transferase [1575 U/L (12 - 64 U/L)] and alkaline phosphatase [271 U/L (40 - 150 U/L)]. Computed tomography showed a 17 mm hypervascular lesion in the confluence of the right and left hepatic ducts, with bile duct ectasia and right liver lobe atrophy. The patient was initially managed as having a Klatskin tumour and underwent right hepatectomy. Histology showed a spindle cell proliferation with an inflammatory infiltrate of lymphocytes, plasma cells and collagen-rich stroma, consistent with an inflammatory myofibroblastic tumour. He was discharged 30 days after admission, and nine months later remains asymptomatic. His liver function tests have normalized and follow-up tests are unremarkable.

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Published

2022-02-07

How to Cite

1.
Almeida e Sousa M, Carvalho A, Mega R, Bilhim T. Inflammatory Myofibroblastic Tumour of the Common Bile Duct. Acta Med Port [Internet]. 2022 Feb. 7 [cited 2023 Feb. 7];35(10):765-9. Available from: https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/16976

Issue

Section

Case Report