Life-Threatening Wunderlich Syndrome Associated with Apixaban and the Complexity of Anticoagulation Management in Bleeding Patients: A Case Report

Authors

  • Sérgio Maltês Cardiology Department. Hospital de Santa Cruz. Centro Hospitalar Lisboa Ocidental. Lisbon.
  • Cristina Carvalho Gouveia Internal Medicine Department. Hospital de São Francisco Xavier. Centro Hospitalar Lisboa Ocidental. Lisbon.
  • Filipa Serrazina Neurology Department. Hospital de Egas Moniz. Centro Hospitalar Lisboa Ocidental. Lisbon.
  • Marta Rebelo Intensive Care Department. Hospital de Egas Moniz. Centro Hospitalar Lisboa Ocidental. Lisbon.

DOI:

https://doi.org/10.20344/amp.16941

Keywords:

Acute Kidney Injury, Anticoagulants/adverse effects, Hemorrage, Kidney Diseases/chemically induced, Rupture, Spontaneous

Abstract

Wunderlich syndrome is a rare and possibly life-threatening haemorrhagic syndrome presenting as spontaneous nontraumatic renal rupture with subcapsular and perinephric haemorrhage. Apixaban, a direct oral anticoagulant recommended in patients with atrial fibrillation, has previously been associated with atraumatic solid organ rupture but, to date, no case of apixaban-related Wunderlich syndrome has been reported. We report a rare case of Wunderlich syndrome associated with apixaban while addressing the difficulties face by clinicians when managing anticoagulation in bleeding patients.

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References

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Published

2022-07-08

How to Cite

1.
Maltês S, Carvalho Gouveia C, Serrazina F, Rebelo M. Life-Threatening Wunderlich Syndrome Associated with Apixaban and the Complexity of Anticoagulation Management in Bleeding Patients: A Case Report. Acta Med Port [Internet]. 2022 Jul. 8 [cited 2024 Oct. 6];36(3):206-9. Available from: https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/16941

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Section

Case Report