Natural Tolerance Development to Peach in a Child with Lipid Transfer Protein Allergy

Authors

  • Joana Queirós Gomes Allergy Department. Centro Hospitalar Vila Nova de Gaia/Espinho. Vila Nova de Gaia. https://orcid.org/0000-0002-2228-2657
  • Ana Rita Presa Allergy Department. Centro Hospitalar Vila Nova de Gaia/Espinho. Vila Nova de Gaia.
  • Ana Reis Ferreira Allergy Department. Centro Hospitalar Vila Nova de Gaia/Espinho. Vila Nova de Gaia.

DOI:

https://doi.org/10.20344/amp.16328

Keywords:

Carrier Proteins/immunology, Child, Food Hypersensitivity, Fruit Proteins/immunology, Immune Tolerance, Prunus Persica

Abstract

Non-specific lipid transfer proteins (LTPs), present in multiple plant foods and pollens, are the predominant allergen in peach allergy in the Mediterranean region and may induce life-threatening allergic reactions. Although reasonably studied in adults, LTP allergy has been rarely described in children, and to the best of the author’s knowledge, natural tolerance development during childhood to this allergen has not been reported to date. The authors reported the case of a 21 month-old boy who presented urticaria and facial edema 15 minutes after eating a peach. Sensitization to peach LTP was confirmed by skin prick tests and specific IgE. At the age of 32 months, skin prick tests and specific IgE to peach LTP were negative, so a food challenge was performed. The child tolerated one medium-sized peach. Peach and peach-related fruits were reintroduced in the child’s diet. The authors discuss the relevance of regular allergy workup and dietary recommendations in children with LTP allergy.

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Author Biographies

Joana Queirós Gomes, Allergy Department. Centro Hospitalar Vila Nova de Gaia/Espinho. Vila Nova de Gaia.

Allergy department

Ana Rita Presa, Allergy Department. Centro Hospitalar Vila Nova de Gaia/Espinho. Vila Nova de Gaia.

Allergy department

Ana Reis Ferreira, Allergy Department. Centro Hospitalar Vila Nova de Gaia/Espinho. Vila Nova de Gaia.

Allergy department

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Published

2022-09-01

How to Cite

1.
Queirós Gomes J, Presa AR, Reis Ferreira A. Natural Tolerance Development to Peach in a Child with Lipid Transfer Protein Allergy. Acta Med Port [Internet]. 2022 Sep. 1 [cited 2024 Mar. 28];35(9):669-71. Available from: https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/16328

Issue

Section

Case Report