The Role of Molecular Allergens in the Diagnosis of Cat-Pork Syndrome: An Unusual Case Report


  • Joana Barradas Lopes Department of Immunoallergology. Centro Hospitalar de Vila Nova de Gaia/Espinho. Vila Nova de Gaia.
  • Moises Labrador-Horrilo Department of Allergy. Hospital Vall de’Hebron UAB. Barcelona.
  • Borja Bartolomé Research and Development Department of Roxall. Bilbao.
  • Leonor Cunha Department of Immunoallergology. Centro Hospital Universitário do Porto. Porto.



Cats/immunology, Food Hypersensitivity/immunology, Meat/adverse effects, Serum Albumin/immunology, Swine/immunology


Cat-pork syndrome is a rare condition, with few cases reported in the literature. This syndrome is justified by the homology between serum albumins from cat and pork. Evidence suggests that a primary sensitization to cat serum albumin Fel d 2 occurs, followed by allergic reactions after ingestion of pork meat containing serum albumin Sus s 1. Due to homology between other mammalian serum albumins, reactions with other meats can also be present. We report a well-documented case report of a patient with cat-pork syndrome, with initial mild and non-specific manifestations to well-cooked pork that were overlooked. Component resolved diagnosis was essential to establish the diagnosis, which confirmed the involvement of Fed 2 and Sus s 1, but less relevant in helping to define avoidance diets, since the sensitization profile was not in accordance with clinical manifestations.


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How to Cite

Barradas Lopes J, Labrador-Horrilo M, Bartolomé B, Cunha L. The Role of Molecular Allergens in the Diagnosis of Cat-Pork Syndrome: An Unusual Case Report. Acta Med Port [Internet]. 2022 May 2 [cited 2024 May 28];35(5):388-91. Available from:



Case Report