Hereditary Thrombophilia and Pregnancy: Thrombotic Risk and Pregnancy Outcome
DOI:
https://doi.org/10.20344/amp.1362Abstract
Thromboembolic disease and obstetric complications related to ischemia of the placenta are currently the major causes of maternalmortality and morbidity. Thrombophilia been implicated in their aetiology and the magnitude of the risk depends on the type of thrombophilia.As the evidence is still unclear and controversial, questions about the clinical management of pregnant women with thrombophiliaare a daily issue. We aim to review, bearing in mind the consensus and controversies, the impact of inherited thrombophilia in the risk ofthrombosis related to pregnancy and of obstetric complications. Moreover, the diagnostic, preventive and therapeutic approach duringpregnancy and puerperium, including the role of antithrombotic pharmacopoeia available, will be discussed.
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