Adult nesidioblastosis.


  • Vítor A Branco Serviço de Medicina III, Hospitais da Universidade de Coimbra, Coimbra.
  • Rui M Santos
  • M Augusta Cipriano
  • Guilherme Tralhão
  • M Otero
  • José A Moura
  • F Castro Sousa
  • Armando Porto



In adults, endogenous hyperinsulinemic hypoglycaemia is almost invariably due to insulinoma. The authors describe a 29 year old patient with repeated postprandial symptomatic hypoglycaemias and negative prolonged fast test. Distal pancreatectomy was performed, directed by positive arteriographic testing. Histological examination revealed pancreatic nesidioblastosis and no tumoral lesion. Distinct pathogenetic, clinical, diagnostic and therapeutic aspects of this rare disease in the adult are reviewed.


Download data is not yet available.

How to Cite

Branco VA, Santos RM, Cipriano MA, Tralhão G, Otero M, Moura JA, Sousa FC, Porto A. Adult nesidioblastosis. Acta Med Port [Internet]. 2003 Dec. 31 [cited 2023 Dec. 1];16(6):465-70. Available from:



Arquivo Histórico