XXIV Highlights AMP-S

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Originals

Bone turnover and periprosthetic bone loss after cementless total hip arthroplasty can be restored by zoledronic acid: a prospective, randomized, open-label, controlled trial
Huang TW, Wang CJ, Shih HN, et al. Bone turnover and periprosthetic bone loss after cementless total hip arthroplasty can be restored by zoledronic acid: a prospective, randomized, open-label, controlled trial. BMC Musculoskelet Disord. 2017 May 22;18(1):209. doi: 10.1186/s12891-017-1577-2. (Original) PMID: 28532408

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«Although the loss of bone mineral density (BMD) after total hip arthroplasty (THA) is a known problem, it remains unresolved. This study prospectively examined the effect of zoledronic acid (ZA) on bone turnover and BMD after cementless THA.»

Review

Topical antimicrobial agents for treating foot ulcers in people with diabetes
Dumville JC, Lipsky BA, Hoey C, et al. Topical antimicrobial agents for treating foot ulcers in people with diabetes. Cochrane Database Syst Rev. 2017 Jun 14;6:CD011038. doi: 10.1002/14651858.CD011038.pub2. (Review) PMID: 28613416

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«People with diabetes are at high risk for developing foot ulcers, which often become infected. These wounds, especially when infected, cause substantial morbidity. Wound treatments should aim to alleviate symptoms, promote healing, and avoid adverse outcomes, especially lower extremity amputation. Topical antimicrobial therapy has been used on diabetic foot ulcers, either as a treatment for clinically infected wounds, or to prevent infection in clinically uninfected wounds.»

Pre-admission antibiotics for suspected cases of meningococcal disease
Sudarsanam TD, Rupali P, Tharyan P, et al. Pre-admission antibiotics for suspected cases of meningococcal disease. Cochrane Database Syst Rev. 2017 Jun 14;6:CD005437. doi: 10.1002/14651858.CD005437.pub4. (Review) PMID: 28613408

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«Meningococcal disease can lead to death or disability within hours after onset. Pre-admission antibiotics aim to reduce the risk of serious disease and death by preventing delays in starting therapy before confirmation of the diagnosis.»

Exercise interventions for cerebral palsy
Ryan JM, Cassidy EE, Noorduyn SG, et al. Exercise interventions for cerebral palsy. Cochrane Database Syst Rev. 2017 Jun 11;6:CD011660. doi: 10.1002/14651858.CD011660.pub2. (Review) PMID: 28602046

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«Exercise is defined as a planned, structured and repetitive activity that aims to improve fitness, and it is a commonly used intervention for people with cerebral palsy (CP). Aerobic and resistance training may improve activity (i.e. the ability to execute a task) and participation (i.e. involvement in a life situation) through their impact on the primary impairments of CP.»